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Articles (70)
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Cellular uptake and trafficking of antisense oligonucleotides

Crooke, Stanley T, Wang, Shiyu, Vickers, Timothy A, Shen, Wen, Liang, Xue-hai

Journal:

Nature Biotechnology

Année:

2017

Langue:

english

Fichier:

PDF, 4.34 MB

english, 2017

A monocular structured light vision method for pose determination of large non-cooperative satellites

Gao, Xue-Hai, Liang, Bin, Pan, Le, Li, Zhi-Heng, Zhang, Ying-Chun

Journal:

International Journal of Control, Automation and Systems

Année:

2016

Langue:

english

Fichier:

PDF, 956 KB

english, 2016

Effect of quenching rate on microstructure and stress corrosion cracking of 7085 aluminum alloy

Song-yi CHEN, Kang-hua CHEN, Guo-sheng PENG, Xin LIANG, Xue-hai CHEN

Journal:

Transactions of Nonferrous Metals Society of China

Année:

2012

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2012

Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides

Wang, Shiyu, Sun, Hong, Tanowitz, Michael, Liang, Xue-hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2016

Langue:

english

Fichier:

PDF, 14.15 MB

english, 2016

Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotides

Wang, Shiyu, Sun, Hong, Tanowitz, Michael, Liang, Xue-hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2017

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2017

Effects of deferoxamine mesylate on hematoma and perihematoma edema after traumatic intracerebral hemorrhage

yu, jian, Yuan, Qiang, Sun, Yi-rui, wu, xing, Du, Zhou-ying, Li, Zhi-qi, Wu, Xue-hai, Zhou, Liang-fu, Wu, Gang, hu, jin

Journal:

Journal of Neurotrauma

Année:

2017

Langue:

english

Fichier:

PDF, 418 KB

english, 2017

Study on GMZ bentonite-sand mixture by undrained triaxial tests

Sun, Wen-jing, Chen, Chao, Liu, Shi-qing, Sun, De-an, Liang, Xue-hai, Tan, Yun-Zhi, Fatahi, Behzad, Delage, P., Cui, Y.-J., Ghabezloo, S., Pereira, J.-M., Tang, A.-M.

Journal:

E3S Web of Conferences

Année:

2016

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2016

Uncovering the action of ethanol controlled crystallization of 3,4-bis(3-nitrofurazan-4-yl)furoxan crystal: A molecular dynamics study

Song, Liang, Zhao, Feng-Qi, Xu, Si-Yu, Ju, Xue-Hai

Journal:

Journal of Molecular Graphics and Modelling

Année:

2019

Langue:

english

Fichier:

PDF, 6.08 MB

english, 2019

Antisense drug discovery and development technology considered in a pharmacological context

Crooke, Stanley T., Liang, Xue-hai, Crooke, Rosanne M., Baker, Brenda F., Geary, Richard S.

Journal:

Biochemical Pharmacology

Année:

2020

Fichier:

PDF, 8.21 MB

2020

A hybrid algorithm of underwater structure vibration and acoustic radiation-propagation in ocean acoustic channel

Duan, Jia-xi, Zhang, Lin, Da, Liang-long, Sun, Xue-hai, Chen, Wen-jing

Journal:

International Journal of Naval Architecture and Ocean Engineering

Année:

2020

Fichier:

PDF, 6.34 MB

2020

Center-of-gravity fuzzy systems based on normal fuzzy implications

Xue-hai Yuan, Zeng-liang Liu, E. Stanley Lee

Journal:

Computers & Mathematics with Applications

Année:

2011

Langue:

english

Fichier:

PDF, 577 KB

english, 2011

Derivation of a general formula and a general area method for latent heat via differential thermal analysis

En-Yong Ding, Xue-Hai Liang

Journal:

Thermochimica Acta

Année:

1998

Langue:

english

Fichier:

PDF, 151 KB

english, 1998

Computational investigation on 2,6-diamino-3,5-dinitropyridine-1-oxide crystal

Zhi-Wei He, Su-Qin Zhou, Xue-Hai Ju, Zu-Liang Liu

Journal:

Structural Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 422 KB

english, 2010

Effect of Xuezhikang on Cardiovascular Events and Mortality in Elderly Patients with a History of Myocardial Infarction: A Subgroup Analysis of Elderly Subjects from the China Coronary Secondary Prevention Study

Ping Ye, Zong-Liang Lu, Bao-min Du, Zuo Chen, Yang-Feng Wu, Xue-Hai Yu, Yu-Cheng Zhao, for the CCSPS Investigators

Journal:

Journal of the American Geriatrics Society

Année:

2007

Langue:

english

Fichier:

PDF, 123 KB

english, 2007

Ion-channels reconstituted into lipid bilayer from human sperm plasma membrane

Yu-Liang Shi, Xue-Hai Ma

Journal:

Molecular Reproduction and Development

Année:

1998

Langue:

english

Fichier:

PDF, 125 KB

english, 1998

Small nucleolar RNAs that guide modification in trypanosomatids: repertoire, targets, genome organisation, and unique functions

Shai Uliel, Xue-hai Liang, Ron Unger, Shulamit Michaeli

Journal:

International Journal for Parasitology

Année:

2004

Langue:

english

Fichier:

PDF, 336 KB

english, 2004

Analysis of spliceosomal complexes in Trypanosoma brucei and silencing of two splicing factors Prp31 and Prp43

Xue-hai Liang, Qing Liu, Li Liu, Christian Tschudi, Shulamit Michaeli

Journal:

Molecular and Biochemical Parasitology

Année:

2006

Langue:

english

Fichier:

PDF, 516 KB

english, 2006

Effects of ADP, DTT, and Mg2+on the Ion-Conductive Property of Chloroplast H+-ATPase(CF0-CF1) Reconstituted into Bilayer Membrane

Xue-Hai Ma, Yu-Liang Shi

Journal:

Biochemical and Biophysical Research Communications

Année:

1997

Langue:

english

Fichier:

PDF, 81 KB

english, 1997

Impact of long-term Xuezhikang therapy on cardiovascular events in high-risk patients with nonspecific, preexisting abnormal liver tests: A post-hoc analysis from Chinese Coronary Secondary Prevention Study (CCSPS)

Jian-Jun Li, Zong-Liang Lu, Wen-Rong Kou, Roberto Bolli, Zuo Chen, Yang-Feng Wu, Xue-Hai Yu, Yu-Cheng Zhao

Journal:

International Journal of Cardiology

Année:

2012

Langue:

english

Fichier:

PDF, 182 KB

english, 2012

rRNA Modifications in an Intersubunit Bridge of the Ribosome Strongly Affect Both Ribosome Biogenesis and Activity

Xue-hai Liang, Qing Liu, Maurille J. Fournier

Journal:

Molecular Cell

Année:

2007

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2007

Phase transition properties of polyethylene glycol-cellulose blends and their miscibility in mixed solvents

Guo, Yuan-Qiang, Liang, Xue-Hai

Journal:

Journal of Macromolecular Science Part B

Année:

1999

Langue:

english

Fichier:

PDF, 474 KB

english, 1999

Crystalline-Amorphous Phase Transition of Poly(ethylene Glycol)/Cellulose Blend

Liang, Xue-Hai, Guo, Yuan-Qiang, Gu, Lian-Zhen, Ding, En-Yong

Journal:

Macromolecules

Année:

1995

Langue:

english

Fichier:

PDF, 470 KB

english, 1995

Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells

Liang, Xue-hai, Hart, Christopher E., Crooke, Stanley T.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Année:

2013

Langue:

english

Fichier:

PDF, 2.30 MB

english, 2013

RNA helicase A is not required for RISC activity

Liang, Xue-hai, Crooke, Stanley T.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013

Should Stage T2 Esophageal Squamous Cell Carcinoma Be Subclassified?

Guo, Wei, Xiao, Hua-Liang, Ma, Zheng, Liu, Hui-Jun, Wang, Ying-Jian, Mei, Long-Yong, Liu, Xue-Hai, Jiang, Yao-Guang, Wang, Ru-Wen

Journal:

Annals of Surgical Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 246 KB

english, 2014

Beneficial Impact of Xuezhikang on Cardiovascular Events and Mortality in Elderly Hypertensive Patients With Previous Myocardial Infarction From the China Coronary Secondary Prevention Study (CCSPS)

Li, Jian-Jun, Lu, Zong-Liang, Kou, Wen-Rong, Chen, Zuo, Wu, Yang-Feng, Yu, Xue-Hai, Zhao, Yu-Cheng

Journal:

Journal of Clinical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 268 KB

english, 2009

Impact of Xuezhikang on coronary events in hypertensive patients with previous myocardial infarction from the China Coronary Secondary Prevention Study (CCSPS)

Li, Jian-Jun, Lu, Zong-Liang, Kou, Wen-Rong, Chen, Zuo, Wu, Yang-Feng, Yu, Xue-Hai, Zhao, Yu-Cheng

Journal:

Annals of Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 224 KB

english, 2010

Low-dose recombinant factor VIIa for reversing coagulopathy in patients with isolated traumatic brain injury

Yuan, Qiang, Wu, Xing, Du, Zhuo-Ying, Sun, Yi-Rui, Yu, Jian, Li, Zhi-Qi, Wu, Xue-Hai, Mao, Ying, Zhou, Liang-Fu, Hu, Jin

Journal:

Journal of Critical Care

Année:

2015

Langue:

english

Fichier:

PDF, 213 KB

english, 2015

X-ray phase analysis of polymer mixtures using a new amorphous scattering expression

Liang, Xue-Hai, Lin, Rui-Xun, Gu, Lian-Zen, Tao, Hua, Lin, Jian-Ming

Journal:

Journal of Macromolecular Science Part B

Année:

1991

Langue:

english

Fichier:

PDF, 500 KB

english, 1991

Long-Term Effects of Xuezhikang on Blood Pressure in Hypertensive Patients with Previous Myocardial Infarction: Data from the Chinese Coronary Secondary Prevention Study (CCSPS)

Li, Jian-Jun, Lu, Zong-Liang, Kou, Wen-Rong, Chen, Zuo, Wu, Yang-Feng, Yu, Xue-Hai, Zhao, Yu-Cheng

Journal:

Clinical and Experimental Hypertension

Année:

2010

Langue:

english

Fichier:

PDF, 156 KB

english, 2010

Telmisartan reduces atrial arrhythmia susceptibility through the regulation of RAS–ERK and PI3K–Akt–eNOS pathways in spontaneously hypertensive rats

Wang, Wei-wei, Zhang, Fei-long, Chen, Jian-hua, Chen, Xue-hai, Fu, Fa-yuan, Tang, Mi-rong, Chen, Liang-long

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2015

Fichier:

PDF, 4.36 MB

2015

The miscibility of cellulose-polyethylene glycol blends

Guo, Yuan-Qiang, Lclc, Xue-Hai Liang

Journal:

Journal of Macromolecular Science Part B

Année:

1999

Langue:

english

Fichier:

PDF, 337 KB

english, 1999

RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery

Lima, Walt F., De Hoyos, Cheryl L., Liang, Xue-hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.34 MB

english, 2016

Mis-targeted methylation in rRNA can severely impair ribosome synthesis and activity

Liu, Ben, Liang, Xue-hai, Piekna-Przybylska, Dorota, Liu, Qing, Fournier, Maurille J.

Journal:

RNA Biology

Année:

2008

Langue:

english

Fichier:

PDF, 759 KB

english, 2008

Hsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2′-modifications and enhances antisense activity

Liang, Xue-Hai, Shen, Wen, Sun, Hong, Kinberger, Garth A., Prakash, Thazha P., Nichols, Joshua G., Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2016

Langue:

english

Fichier:

PDF, 9.55 MB

english, 2016

Theoretical investigations on charge transfer properties of fluorinated perylene diimides

Liang, Meng, Yin, Jun, Chaitanya, Kadali, Ju, Xue-Hai

Journal:

Journal of Theoretical and Computational Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 533 KB

english, 2016

A Fuzzy Trustworthiness System with Probability Presentation Based on Center-of-gravity Method

Zhong, Yu-Bin, Liu, Zeng-Liang, Yuan, Xue-Hai

Journal:

Annals of Data Science

Année:

2015

Langue:

english

Fichier:

PDF, 723 KB

english, 2015

Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

Lima, Walt F., Murray, Heather M., Damle, Sagar S., Hart, Christopher E., Hung, Gene, De Hoyos, Cheryl Li, Liang, Xue-Hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2016

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2016

Xuezhikang, An Extract of Cholestin, Reduces Cardiovascular Events in Type 2 Diabetes Patients With Coronary Heart Disease: Subgroup Analysis of Patients With Type 2 Diabetes From China Coronary Secondary Prevention Study (CCSPS)

Zhao, Shui-ping, Lu, Zong-liang, Du, Bao-min, Chen, Zuo, Wu, Yang-feng, Yu, Xue-hai, Zhao, Yu-cheng, Liu, Ling, Ye, Hui-jun, Wu, Zhi-hong

Journal:

Journal of Cardiovascular Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 64 KB

english, 2007

Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames

Liang, Xue-hai, Shen, Wen, Sun, Hong, Migawa, Michael T, Vickers, Timothy A, Crooke, Stanley T

Journal:

Nature Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus

Liang, Xue-Hai, Sun, Hong, Nichols, Joshua G., Crooke, Stanley T.

Journal:

Molecular Therapy

Année:

2017

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2017

Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels

Liang, Xue-hai, Sun, Hong, Shen, Wen, Wang, Shiyu, Yao, Joyee, Migawa, Michael T., Bui, Huynh-Hoa, Damle, Sagar S., Riney, Stan, Graham, Mark J., Crooke, Rosanne M., Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2017

Langue:

english

Fichier:

PDF, 3.15 MB

english, 2017

Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops

Shen, Wen, Sun, Hong, De Hoyos, Cheryl L., Bailey, Jeffrey K., Liang, Xue-hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2017

Langue:

english

Fichier:

PDF, 11.51 MB

english, 2017

Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides

Bailey, Jeffrey K., Shen, Wen, Liang, Xue-hai, Crooke, Stanley T.

Journal:

Nucleic Acids Research

Année:

2017

Langue:

english

Fichier:

PDF, 10.33 MB

english, 2017

Acute hepatotoxicity of 2′ fluoro-modified 5–10–5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins

Shen, Wen, De Hoyos, Cheryl L, Sun, Hong, Vickers, Timothy A, Liang, Xue-hai, Crooke, Stanley T

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 10.37 MB

english, 2018

Translation can affect the antisense activity of RNase H1-dependent oligonucleotides targeting mRNAs

Liang, Xue-Hai, Nichols, Joshua G, Sun, Hong, Crooke, Stanley T

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2018

Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides

Wang, Shiyu, Allen, Nickolas, Vickers, Timothy A, Revenko, Alexey S, Sun, Hong, Liang, Xue-hai, Crooke, Stanley T

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 6.43 MB

english, 2018

COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways

Liang, Xue-hai, Sun, Hong, Nichols, Joshua G, Allen, Nickolas, Wang, Shiyu, Vickers, Timothy A, Shen, Wen, Hsu, Chih-Wei, Crooke, Stanley T

Journal:

Nucleic Acids Research

Année:

2018

Langue:

english

Fichier:

PDF, 10.32 MB

english, 2018

Membrane Destabilization Induced by Lipid Species Increases Activity of Phosphorothioate-Antisense Oligonucleotides

Wang, Shiyu, Allen, Nickolas, Liang, Xue-hai, Crooke, Stanley T.

Journal:

Molecular Therapy — Nucleic Acids

Année:

2018

Langue:

english

Fichier:

PDF, 4.42 MB

english, 2018

The correlation of pulmonary arterial hypertension with late recurrence of paroxysmal atrial fibrillation after catheter ablation

Zhang, Yan-Qun, Zhang, Fei-Long, Wang, Wei-Wei, Chen, Xue-Hai, Chen, Jian-Hua, Chen, Liang-Long

Journal:

Journal of Thoracic Disease

Année:

2018

Langue:

english

Fichier:

PDF, 256 KB

english, 2018